The ESF1 Antibody (PAC048734) is a polyclonal antibody designed for research on ESF1, a protein involved in RNA processing and gene expression regulation. The antibody, produced in rabbits, is highly specific and reactive with human samples, making it suitable for various applications such as Western blotting and immunohistochemistry.ESF1, also known as essential splicing factor 1, plays a crucial role in the splicing of pre-mRNA during gene expression. Its functions in regulating alternative splicing and mRNA processing make it a key player in gene regulation and cellular function. Studies have shown its involvement in various biological processes, including cell growth, differentiation, and development.
The ESF1 Antibody is a valuable tool for researchers in molecular biology and genetics who are studying RNA processing and gene expression regulation. Its high specificity and reactivity make it ideal for investigating the function and localization of ESF1 in different cell types and tissues. By understanding the role of ESF1 in gene expression, researchers can gain insights into potential therapeutic targets for diseases related to abnormal RNA processing and gene regulation.
ESF1: May constitute a novel regulatory system for basal transcription. Negatively regulates ABT1. Belongs to the ESF1 family.Protein type: Nucleolus; Transcription, coactivator/corepressorChromosomal Location of Human Ortholog: 20p12.1Cellular Component: nucleoplasm; extracellular space; nucleolusBiological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent
