The ERAS Antibody (PAC04072) is a highly specific and sensitive tool for studying the ERAS protein, which is involved in regulating cell growth and proliferation. This polyclonal antibody, produced in rabbits, is particularly effective for detecting ERAS in human samples and is validated for use in Western blot applications.ERAS, a member of the RAS oncogene family, has been linked to various cellular processes, including cell differentiation and survival. Its aberrant expression has been implicated in the development and progression of cancer, making it a promising target for cancer research. The ERAS Antibody enables researchers to investigate the role of ERAS in cancer biology and potentially identify new therapeutic strategies for treating cancer.
Furthermore, the ERAS Antibody can be utilized in studies focusing on cell signaling pathways, as ERAS is known to interact with several key signaling molecules. By understanding the molecular mechanisms involving ERAS, researchers can gain insights into the regulation of cell growth and potentially uncover novel targets for intervention in various diseases.Overall, the ERAS Antibody is a valuable tool for researchers interested in studying the function and significance of the ERAS protein in both basic science and translational research settings. Its high specificity and sensitivity make it an essential component for exploring the role of ERAS in cancer and other disease contexts.
Antibody Name:
ERAS Antibody
Antibody SKU:
PACO04072
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human E-Ras.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ERas: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the tumor-like growth properties of embryonic stem cells. Belongs to the small GTPase superfamily. Ras family.Protein type: G protein, monomeric, Ras; G protein, monomeric; G proteinChromosomal Location of Human Ortholog: Xp11.23
UniProt Protein Details:
NCBI Summary:
This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance. [provided by RefSeq, Dec 2012]
