The EPS8L2 Polyclonal Antibody (PACO09117) is a valuable tool for researchers studying EPS8L2, a protein involved in cell signaling and cytoskeleton organization. This antibody, produced in rabbits, exhibits high specificity for human samples and is suitable for use in Western blot applications. By binding to the EPS8L2 protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for investigations in cell biology and cancer research.EPS8L2, a member of the EPS8 protein family, has been implicated in diverse cellular processes such as cell proliferation, migration, and survival.
Its involvement in these pathways suggests a potential role in cancer development and progression, making EPS8L2 a promising target for therapeutic interventions. By studying the function and regulation of EPS8L2, researchers can gain valuable insights into its impact on disease progression and identify novel treatment strategies for cancer and other pathologies.
EPS8L2: Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. Belongs to the EPS8 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: GEFs; Actin-binding; GEFs, Rac/RhoChromosomal Location of Human Ortholog: 11p15.5Cellular Component: cytoplasm; plasma membrane; protein complex; vesicleMolecular Function: actin binding; Rac guanyl-nucleotide exchange factor activity; Rho guanyl-nucleotide exchange factor activityBiological Process: regulation of Rho protein signal transduction; Rho protein signal transduction
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the EPS8 gene family. The encoded protein, like other members of the family, is thought to link growth factor stimulation to actin organization, generating functional redundancy in the pathways that regulate actin cytoskeletal remodeling. [provided by RefSeq, Dec 2008]
