ENTPD7 Antibody (PACO26493)
- SKU:
- PACO26493
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
ENTPD7 Antibody (PACO26493)
The ENTPD7 Polyclonal Antibody (PACO26493) is a specialized research tool designed for studying ENTPD7, a key enzyme involved in nucleotide metabolism and cellular signaling. This antibody, produced in rabbits, has been rigorously tested for its reactivity with human samples and is optimized for use in Western blotting applications. By specifically recognizing the ENTPD7 protein, researchers can accurately detect and analyze its expression in various cell types, making it an invaluable tool for investigations in molecular biology and cell signaling pathways.
ENTPD7, also known as nucleoside diphosphate phosphohydrolase 7, plays a critical role in regulating nucleotide metabolism and purinergic signaling, which are essential for cellular functions such as cell proliferation and energy metabolism. Understanding the function and regulation of ENTPD7 is crucial for unraveling its role in various physiological processes and diseases. Research on ENTPD7 could provide insights into potential therapeutic targets for conditions related to nucleotide dysregulation, such as cancer and metabolic disorders.
| Antibody Name: | ENTPD7 Antibody (PACO26493) |
| Antibody SKU: | PACO26493 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Ectonucleoside triphosphate diphosphohydrolase 7 protein (51-350AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescent analysis of Hela cells using PACO26493 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Western Blot Positive WB detected in: Hela whole cell lysate, Mouse heart tissue, Mouse spleen tissue, Mouse lung tissue, Mouse kidney tissue All lanes: ENTPD7 antibody at 2.8µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 69 kDa Observed band size: 69 kDa . |
| Background: | Preferentially hydrolyzes nucleoside 5'-triphosphates. The order of activity with respect to possible substrates is UTP > GTP > CTP. |
| Synonyms: | Ectonucleoside triphosphate diphosphohydrolase 7 (NTPDase 7) (EC 3.6.1.-) (Lysosomal apyrase-like protein 1), ENTPD7, LALP1 |
| UniProt Protein Function: | ENTPD7: Preferentially hydrolyzes nucleoside 5'-triphosphates. The order of activity with respect to possible substrates is UTP > GTP > CTP. Belongs to the GDA1/CD39 NTPase family.Protein type: Membrane protein, multi-pass; Hydrolase; Membrane protein, integral; EC 3.6.1.-Chromosomal Location of Human Ortholog: -Cellular Component: cytoplasmic vesicle membrane; integral to membraneMolecular Function: hydrolase activity; metal ion bindingBiological Process: metabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9NQZ7 |
| NCBI GenInfo Identifier: | 74752912 |
| NCBI Gene ID: | 57089 |
| NCBI Accession: | Q9NQZ7.1 |
| UniProt Secondary Accession: | Q9NQZ7,B2RB83, B3KP21, D3DR64 |
| UniProt Related Accession: | Q9NQZ7 |
| Molecular Weight: | 68,960 Da |
| NCBI Full Name: | Ectonucleoside triphosphate diphosphohydrolase 7 |
| NCBI Synonym Full Names: | ectonucleoside triphosphate diphosphohydrolase 7 |
| NCBI Official Symbol: | ENTPD7Â Â |
| NCBI Official Synonym Symbols: | LALP1Â Â |
| NCBI Protein Information: | ectonucleoside triphosphate diphosphohydrolase 7; NTPDase 7; lysosomal apyrase-like protein 1 |
| UniProt Protein Name: | Ectonucleoside triphosphate diphosphohydrolase 7 |
| UniProt Synonym Protein Names: | Lysosomal apyrase-like protein 1 |
| Protein Family: | Ectonucleoside triphosphate diphosphohydrolase |
| UniProt Gene Name: | ENTPD7Â Â |
| UniProt Entry Name: | ENTP7_HUMAN |
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