The ENTPD7 Antibody (PAC016683) is a polyclonal antibody designed for research involving ENTPD7, an enzyme involved in purinergic signaling and regulation of extracellular ATP levels. This antibody, generated in rabbits, has high reactivity with human samples and has been validated for use in various applications, including Western blot and immunofluorescence.ENTPD7 is a critical enzyme that plays a key role in purinergic signaling pathways, which are involved in a variety of biological processes, such as inflammation, immune response, and cancer progression. Understanding the function and regulation of ENTPD7 is essential for studying these processes and developing potential therapies targeting purinergic signaling in diseases like cancer and autoimmune disorders.
With its high specificity and sensitivity, the ENTPD7 Antibody (PAC016683) is a valuable tool for researchers in the fields of immunology, cancer biology, and purinergic signaling. Its ability to detect ENTPD7 protein expression in various cell types makes it a versatile asset for studying the molecular mechanisms underlying purinergic signaling and its role in disease pathogenesis.
Antibody Name:
ENTPD7 Antibody (PACO16683)
Antibody SKU:
PACO16683
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:50-1:200
Species Reactivity:
Human, Mouse
Immunogen:
Fusion protein of human ENTPD7
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO16683(ENTPD7 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO16683(ENTPD7 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200).
Background:
LALP1 (lysosomal apyrase-like protein 1), also known as ENTPD7 (ectonucleoside triphosphate diphosphohydrolase 7), is a 604 amino acid, multi-pass membrane protein that belongs to the GDA1/CD39 NTPase family. Preferentially hydrolyzing nucleoside 5Â’-triphosphates, LALP1 and has an order of activity with respect to possible substrates, which is UTP > GTP > CTP.
Synonyms:
ectonucleoside triphosphate diphosphohydrolase 7
UniProt Protein Function:
ENTPD7: Preferentially hydrolyzes nucleoside 5'-triphosphates. The order of activity with respect to possible substrates is UTP > GTP > CTP. Belongs to the GDA1/CD39 NTPase family.Protein type: Membrane protein, multi-pass; Hydrolase; Membrane protein, integral; EC 3.6.1.-Chromosomal Location of Human Ortholog: -Cellular Component: cytoplasmic vesicle membrane; integral to membraneMolecular Function: hydrolase activity; metal ion bindingBiological Process: metabolic process
