The Elongation Factor 2 Polyclonal Antibody (CAB2068) is a valuable tool for researchers studying protein synthesis and translation regulation. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. It binds to the Elongation Factor 2 protein, allowing for precise detection and analysis in a variety of cell types, making it ideal for investigations in molecular biology and cellular physiology.Elongation Factor 2 is a critical component of the protein synthesis machinery, facilitating the translocation of ribosomes along mRNA during translation.
Dysregulation of EF2 has been linked to various diseases, including cancer and neurodegenerative disorders, making it an important target for research in these fields. By using the Elongation Factor 2 Polyclonal Antibody, researchers can gain insight into the function and regulation of EF2, leading to potential advancements in therapeutic strategies targeting these diseases.
Product Name:
eEF2 Rabbit Polyclonal Antibody
SKU:
CAB2068
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human eEF2 (NP_001952.1).
This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation.
Purification Method:
Affinity purification
Gene ID:
1938
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using eEF2 antibody (CAB2068) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
