The EHMT2 Polyclonal Antibody is a valuable tool for research involving EHMT2, also known as G9a, a protein involved in epigenetic regulation. This antibody is produced in rabbits and has been validated for use in Western blot applications with human samples. By binding specifically to the EHMT2 protein, this antibody enables researchers to detect and analyze EHMT2 expression in various cell types.EHMT2 is an important histone methyltransferase that plays a role in gene regulation and chromatin remodeling.
Dysregulation of EHMT2 has been implicated in various diseases, including cancer and neurodevelopmental disorders. Therefore, studying EHMT2 expression and activity is crucial for understanding its role in disease pathogenesis and potential therapeutic interventions.Overall, the EHMT2 Polyclonal Antibody is a reliable tool for researchers in the fields of epigenetics, cancer biology, and neurobiology, providing valuable insights into the function of EHMT2 in health and disease.
Product Name:
EHMT2 Polyclonal Antibody
SKU:
CAB2295
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 680-813 of human EHMT2 (NP_006700.3).
This gene encodes a methyltransferase that methylates lysine residues of histone H3. Methylation of H3 at lysine 9 by this protein results in recruitment of additional epigenetic regulators and repression of transcription. This gene was initially thought to be two different genes, NG36 and G9a, adjacent to each other in the HLA locus. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10919
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Jurkat cells, using EHMT2 Rabbit pAb (CAB2295).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
