The DUSP23 Monoclonal Antibody (PAC016209) is a valuable tool for researchers studying DUSP23, a dual-specificity phosphatase with potential implications in cellular signaling pathways. This antibody, developed for human samples, is produced using a monoclonal antibody production method, ensuring high specificity and sensitivity in experimental applications.DUSP23, a member of the dual-specificity phosphatase family, is involved in the regulation of MAP kinase signaling and may play a role in cell growth and differentiation. Its expression has been observed in various tissues and cell types, suggesting a diverse physiological function.
By targeting DUSP23 with this antibody, researchers can investigate its role in cellular processes and potentially discover its involvement in disease pathways.This DUSP23 Monoclonal Antibody is suitable for use in techniques such as Western blotting, immunoprecipitation, and immunofluorescence, allowing for versatile and comprehensive analysis of DUSP23 expression and localization. With its high specificity and sensitivity, this antibody is a valuable asset for researchers interested in exploring the function of DUSP23 in normal physiology and disease states.
Antibody Name:
DUSP23 Antibody (PACO16209)
Antibody SKU:
PACO16209
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:50-1:200
Species Reactivity:
Human, Mouse
Immunogen:
Fusion protein of human DUSP23
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO16209(DUSP23 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO16209(DUSP23 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200).
Background:
Dual specificity protein phosphatase 23, also known as low molecular mass dual specificity phosphatase 3 (LDP-3), is an enzyme that in humans is encoded by the DUSP23 gene.
Synonyms:
dual specificity phosphatase 23
UniProt Protein Function:
Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. Able to enhance activation of JNK and p38 (MAPK14).
