The Dock5 Polyclonal Antibody (PAC041346) is a valuable tool for researchers studying the Dock5 protein, a key regulator of cell migration and immune response. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the Dock5 protein, this antibody allows for the detection and analysis of Dock5 in various cell types, making it an essential component for studies in immunology and cancer research.Dock5 plays a crucial role in the regulation of cell adhesion, migration, and signaling pathways, making it a potential target for therapeutic interventions in diseases such as cancer and inflammatory disorders.
By understanding the function of Dock5, researchers can develop novel treatments that target this protein and its associated pathways, leading to advancements in the fields of oncology and immunology. In summary, the Dock5 Polyclonal Antibody is a powerful tool for scientists looking to further their understanding of Dock5 and its implications in immune regulation and disease progression. Its specificity and reliability make it an essential reagent for research projects aimed at uncovering the role of Dock5 in various cellular processes.
Antibody Name:
DOCK5 Antibody (PACO41346)
Antibody SKU:
PACO41346
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human Dedicator of cytokinesis protein 5 protein (1-200AA)
Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP.
Synonyms:
Dedicator of cytokinesis protein 5, DOCK5
UniProt Protein Function:
DOCK5: Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP. Belongs to the DOCK family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: GAPs, Rac/Rho; Motility/polarity/chemotaxis; GAPsChromosomal Location of Human Ortholog: 8p21.2Cellular Component: cytoplasmMolecular Function: guanyl-nucleotide exchange factor activityBiological Process: positive regulation of GTPase activity; positive regulation of smooth muscle cell migration; small GTPase mediated signal transduction
