DNMT3A Rabbit Polyclonal Antibody (CAB3169)
- SKU:
- CAB3169
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | DNMT3A Rabbit Polyclonal Antibody |
SKU: | CAB3169 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 500-700 of human DNMT3A (NP_072046.2). |
Sequence: | LNVT LEHP LFVG GMCQ NCKN CFLE CAYQ YDDD GYQS YCTI CCGG REVL MCGN NNCC RCFC VECV DLLV GPGA AQAA IKED PWNC YMCG HKGT YGLL RRRE DWPS RLQM FFAN NHDQ EFDP PKVY PPVP AEKR KPIR VLSL FDGI ATGL LVLK DLGI QVDR YIAS EVCE DSIT VGMV RHQG KIMY VGDV RSVT QKHI QEWG P |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:20 |
Synonyms: | TBRS; HESJAS; DNMT3A2; M.HsaIIIA; DNMT3A |
Positive Sample: | Mouse spleen,Mouse skeletal muscle |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 102kDa |
Observed MW: | 95kDa |
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
Purification Method: | Affinity purification |
Gene ID: | 1788 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |