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DNM1L Polyclonal Antibody (CAB21311)

SKU:
CAB21311
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
IF
€129 - €359
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:DNM1L Polyclonal Antibody
SKU:CAB21311
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 437-736 of human DNM1L (NP_036192.2).
Sequence:EEMQ RIIQ HCSN YSTQ ELLR FPKL HDAI VEVV TCLL RKRL PVTN EMVH NLVA IELA YINT KHPD FADA CGLM NNNI EEQR RNRL AREL PSAV SRDK SSKV PSAL APAS QEPS PAAS AEAD GKLI QDSR RETK NVAS GGGG VGDG VQEP TTGN WRGM LKTS KAEE LLAE EKSK PIPI MPAS PQKG HAVN LLDV PVPV ARKL SARE QRDC EVIE RLIK SYFL IVRK NIQD SVPK AVMH FLVN HVKD TLQS ELVG QLYK SSLL DDLL TESE DMAQ RRKE AADM LKAL QGAS QIIA EIRE THLW
Tested Applications:IF/ICC ELISA
Recommended Dilution:IF/ICC,1:50 - 1:200
Synonyms:DLP1; DRP1; DVLP; EMPF; OPA5; EMPF1; DYMPLE; HDYNIV; DNM1L
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Cytoplasmic vesicle, Endomembrane system, Golgi apparatus, Membrane, Mitochondrion outer membrane, Peripheral membrane protein, Peroxisome, clathrin-coated pit, cytosol, secretory vesicle, synaptic vesicle membrane.
Calculated MW:82kDa
Observed MW:Refer to figures

This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.

Purification Method:Affinity purification
Gene ID:10059
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageImmunofluorescence analysis of NIH/3T3 cells using DRP1 Rabbit pAb (CAB21311) at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.

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