The DMRT3 Polyclonal Antibody (PACO58580) is a valuable tool for researchers studying DMRT3, a transcription factor involved in neural development and the formation of neural circuits. Raised in rabbits, this antibody has high reactivity with human samples and has been validated for use in various research applications, including Western blotting. By binding specifically to the DMRT3 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in neuroscience and developmental biology.
DMRT3 is known for its role in determining the fate of neurons and is essential for the proper functioning of the nervous system. Its involvement in neural development makes it a key target for research into neurological disorders, such as spinal cord injuries and neurodevelopmental conditions. Understanding the function of DMRT3 is crucial for advancing our knowledge of neural development and potentially developing therapies to treat these conditions.
Antibody Name:
DMRT3 Antibody (PACO58580)
Antibody SKU:
PACO58580
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:500-1:1000
Species Reactivity:
Human
Immunogen:
Recombinant Human Doublesex- and mab-3-related transcription factor 3 protein (92-224AA)
IHC image of PACO58580 diluted at 1:700 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Background:
Probable transcription factor that plays a role in configuring the spinal circuits controlling stride in vertebrates. Involved in neuronal specification within specific subdivision of spinal cord neurons and in the development of a coordinated locomotor network controlling limb movements. May regulate transcription during sexual development (By similarity).
Synonyms:
Doublesex- and mab-3-related transcription factor 3, DMRT3, DMRTA3
