The Delta-Ctenitoxin PN1A Antibody (PACO34574) is a highly specific antibody designed for research involving the Delta-Ctenitoxin PN1A protein, a toxin known for its potent activity on ion channels. The antibody, raised in rabbits, is validated for use in various experimental applications, including immunofluorescence, immunohistochemistry, and ELISA.Delta-Ctenitoxin PN1A is a peptide toxin found in the venom of the spider Phoneutria nigriventer, known for its ability to modulate voltage-gated calcium channels and sodium channels. Research on Delta-Ctenitoxin PN1A has implications for understanding neuronal function and synaptic transmission, making this antibody a valuable tool for scientists studying neurobiology and ion channel physiology.
By specifically targeting the Delta-Ctenitoxin PN1A protein, this antibody enables researchers to detect and analyze its presence in cell samples, providing insights into the mechanisms by which this toxin interacts with ion channels. Its potential applications in neuroscience and drug development make it a key reagent for studies seeking to understand the impact of Delta-Ctenitoxin PN1A on neuronal signaling and excitability.
Antibody Name:
Delta-ctenitoxin-Pn1a Antibody (PACO34574)
Antibody SKU:
PACO34574
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Phoneutria nigriventer
Immunogen:
Recombinant Phoneutria nigriventer Delta-ctenitoxin-Pn1a protein (35-82AA)
This neurotoxin binds at site 3 of insect voltage-activated sodium channels (Nav) and prolongs evoked axonal action potentials by a slowing down of sodium current inactivation. The toxin inhibits glutamate uptake from rat brain synaptosomes. It is highly toxic to house fly (Musca domestica), toxic to cockroach, but has no effect when intracerebroventricularly injected into mice.
This neurotoxin binds at site 3 of insect voltage-activated sodium channels (Nav) and prolongs evoked axonal action potentials by a slowing down of sodium current inactivation. The toxin inhibits glutamate uptake from rat brain synaptosomes. It is highly toxic to house fly (Musca domestica), toxic to cockroach, but has no effect when intracerebroventricularly injected into mice.
