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DEFA1 Rabbit Polyclonal Antibody (CAB6897)

SKU:
CAB6897
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
  • Immunology Antibodies 2 Anti-DEFA1 Antibody CAB6897
  • Immunology Antibodies 2 Anti-DEFA1 Antibody CAB6897
  • Immunology Antibodies 2 Anti-DEFA1 Antibody CAB6897
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:DEFA1 Rabbit Polyclonal Antibody
SKU:CAB6897
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-94 of human DEFA1 (NP_004075.1).
Sequence:MRTL AILA AILL VALQ AQAE PLQA RADE VAAA PEQI AADI PEVV VSLA WDES LAPK HPGS RKNM ACYC RIPA CIAG ERRY GTCI YQGR LWAF CC
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200
Synonyms:HP1; MRS; DEF1; HP-1; DEFA2; HNP-1; DEFA1
Positive Sample:THP-1,U-937
Conjugate:Unconjugated
Cellular Localization:Secreted.
Calculated MW:10kDa
Observed MW:10kDa

Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.

Purification Method:Affinity purification
Gene ID:1667
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using DEFA1 Rabbit pAb (CAB6897) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.

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