The DCAF4 Polyclonal Antibody (CAB14869) is a valuable tool for researchers studying DCAF4, a protein involved in cell cycle regulation and DNA repair processes. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. It binds specifically to the DCAF4 protein, allowing for accurate detection and analysis in a variety of cell types.DCAF4 is known for its role in mediating substrate specificity of the E3 ubiquitin ligase complex and has been implicated in various cellular processes such as cell division and DNA damage response.
Understanding the function of DCAF4 can provide critical insights into the mechanisms underlying cell growth and genome stability, making this antibody an essential tool for studies in cancer biology, cell biology, and genetics research.Overall, the DCAF4 Polyclonal Antibody is a reliable reagent for investigating the functions and regulatory mechanisms of DCAF4 in cellular processes, making it an indispensable resource for researchers in the fields of molecular biology and cancer research.
Product Name:
DCAF4 Rabbit Polyclonal Antibody
SKU:
CAB14869
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human DCAF4 (NP_056419.2).
This gene encodes a WD repeat-containing protein that interacts with the Cul4-Ddb1 E3 ligase macromolecular complex. Multiple alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
26094
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from U-251MG cells, using DCAF4 Rabbit pAb (CAB14869) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
