CYP7B1 Rabbit Polyclonal Antibody (CAB17872)
- SKU:
- CAB17872
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | CYP7B1 Rabbit Polyclonal Antibody |
SKU: | CAB17872 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CYP7B1 (NP_004811.1). |
Sequence: | MAGE VSAA TGRF SLER LGLP GLAL AAAL LLLA LCLL VRRT RRPG EPPL IKGW LPYL GVVL NLRK DPLR FMKT LQKQ HGDT FTVL LGGK YITF ILDP FQYQ |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | CP7B; CBAS3; SPG5A; CYP7B1 |
Positive Sample: | A-431 |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Microsome membrane, Peripheral membrane protein. |
Calculated MW: | 58kDa |
Observed MW: | 55kDa |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. Mutations in this gene have been associated with hereditary spastic paraplegia (SPG5 or HSP), an autosomal recessive disorder.
Purification Method: | Affinity purification |
Gene ID: | 9420 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |