CYP2R1 Rabbit Polyclonal Antibody (CAB10470)
- SKU:
- CAB10470
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CYP2R1 Rabbit Polyclonal Antibody |
SKU: | CAB10470 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 252-501 of human CYP2R1 (NP_078790.2). |
Sequence: | VVYD FLSR LIEK ASVN RKPQ LPQH FVDA YLDE MDQG KNDP SSTF SKEN LIFS VGEL IIAG TETT TNVL RWAI LFMA LYPN IQGQ VQKE IDLI MGPN GKPS WDDK CKMP YTEA VLHE VLRF CNIV PLGI FHAT SEDA VVRG YSIP KGTT VITN LYSV HFDE KYWR DPEV FHPE RFLD SSGY FAKK EALV PFSL GRRH CLGE HLAR MEMF LFFT ALLQ RFHL HFPH ELVP DLKP RLGM TLQP QPYL ICAE RR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CYP2R1 |
Positive Sample: | Mouse liver,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Microsome membrane, Peripheral membrane protein. |
Calculated MW: | 57kDa |
Observed MW: | 57kDa |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency.
Purification Method: | Affinity purification |
Gene ID: | 120227 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |