The CUTc Polyclonal Antibody (PACO08680) is an essential tool for researchers studying the CUTc protein, a key player in copper transport and homeostasis within cells. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it a reliable option for Western blot experiments. With its ability to bind specifically to CUTc, researchers can accurately detect and analyze the protein in various cell types, which is particularly valuable for investigations in areas such as molecular biology and neurodegenerative diseases.CUTc, also known as Copper Transport Protein C, is crucial for maintaining copper levels within cells and ensuring proper cellular function.
Dysregulation of CUTc has been implicated in diseases such as Wilson's disease and Menkes disease, highlighting its importance in copper metabolism. By studying the role of CUTc, researchers can gain insights into the mechanisms underlying these disorders and potentially identify new therapeutic targets for treatment.Overall, the CUTc Polyclonal Antibody is a valuable resource for scientists interested in exploring the functions of the CUTc protein and its implications in various health conditions. Its reliability and specificity make it a trusted tool for advancing research in the fields of biochemistry, cell biology, and neurology.
cutC copper transporter homolog (E. coli);CUTC;CGI-32;RP11-483F11.3 ;
UniProt Protein Function:
CUTC: a copper binding protein associated with copper homeostasis and transport. Widely expressed in human tissues. Its nuclear and cytoplasmic distribution suggests that it may be a nucleocytoplasmic copper ion shuttle protein.Protein type: CarrierChromosomal Location of Human Ortholog: 10q24.2Cellular Component: cytoplasm; nucleolus; nucleusMolecular Function: copper ion binding; protein bindingBiological Process: protein tetramerization
UniProt Protein Details:
NCBI Summary:
Members of the CUT family of copper transporters are associated with copper homeostasis and are involved in the uptake, storage, delivery, and efflux of copper (Gupta et al., 1995 [PubMed 7635807]; Li et al., 2005 [PubMed 16182249]).[supplied by OMIM, Mar 2008]