The CTDNEP1 Polyclonal Antibody (PAC031964) is a valuable tool for researchers studying CTDNEP1, a protein involved in various cellular processes, including DNA repair and cell cycle regulation. This antibody, produced using rabbits, is highly specific to human samples and has been validated for use in Western blotting applications. By binding to the CTDNEP1 protein, this antibody enables researchers to detect and analyze the protein in different cell types, making it an essential component for studies in molecular biology and cancer research.CTDNEP1, also known as CTD nuclear envelope phosphatase 1, plays a crucial role in maintaining genome stability and cell division.
Dysregulation of CTDNEP1 has been linked to various diseases, including cancer and developmental disorders. Therefore, understanding the function of CTDNEP1 is essential for developing targeted therapies to treat these conditions.Overall, the CTDNEP1 Polyclonal Antibody (PAC031964) offers researchers a reliable tool to study the function of CTDNEP1 and its implications in disease pathology. Its high specificity and versatility make it a valuable asset for any laboratory conducting research in the fields of molecular biology and oncology.
Antibody Name:
CTDNEP1 Antibody (PACO31964)
Antibody SKU:
PACO31964
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human CTD nuclear envelope phosphatase 1 protein (3-244AA)
DULLARD: Serine/threonine protein phosphatase forming with CNEP1R1 an active phosphatase complex that dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at differents levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol. May antagonize BMP signaling. Belongs to the dullard family.Protein type: EC 3.1.3.16; Protein phosphatase, Ser/Thr (non-receptor); Endoplasmic reticulum; Membrane protein, integralChromosomal Location of Human Ortholog: 17p13Cellular Component: cytoplasm; endoplasmic reticulum membrane; nuclear envelope; nuclear membraneMolecular Function: protein binding; protein serine/threonine phosphatase activityBiological Process: mitotic nuclear envelope disassembly; nuclear membrane organization and biogenesis; protein amino acid dephosphorylation
