The CPED1 Polyclonal Antibody (PACO61185) is a valuable tool for researchers studying CPED1, a protein involved in cellular processes such as cell proliferation and differentiation. This antibody, produced in rabbits, has a high specificity for CPED1 in human samples and is suitable for use in Western blotting applications. By targeting the CPED1 protein, this antibody allows for the precise detection and analysis of CPED1 expression in a variety of cell types, making it an essential component in studies related to developmental biology and cellular signaling pathways.CPED1 is known for its role in regulating cell growth and differentiation, making it a key player in processes like embryogenesis and tissue regeneration.
Additionally, CPED1 has been implicated in various diseases, including cancer and developmental disorders, highlighting its importance as a potential therapeutic target. By investigating the function of CPED1 using this antibody, researchers can gain insight into its biological role and its implications for disease pathogenesis, paving the way for the development of targeted therapies aimed at modulating CPED1 activity.
Antibody Name:
CPPED1 Antibody (PACO61185)
Antibody SKU:
PACO61185
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:200-1:500
Species Reactivity:
Human
Immunogen:
Recombinant Human Serine/threonine-protein phosphatase CPPED1 protein (49-186AA)
IHC image of PACO61185 diluted at 1:400 and staining in paraffin-embedded human skeletal muscle tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Background:
Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.
Synonyms:
Serine/threonine-protein phosphatase CPPED1 (EC 3.1.3.16) (Calcineurin-like phosphoesterase domain-containing protein 1) (Complete S-transactivated protein 1), CPPED1, CSTP1
UniProt Protein Function:
CPPED1: Belongs to the metallophosphoesterase superfamily. CPPED1 family. 2 isoforms of the human protein are produced by alternative splicing.