The CPNE2 Polyclonal Antibody (PAC038718) is a powerful tool for researchers studying CPNE2, a calcium-dependent protein involved in various cellular processes. This antibody, produced in rabbits, shows high specificity towards CPNE2 and is suitable for Western blot applications with human samples. By binding to the CPNE2 protein, this antibody allows for precise detection and analysis in a range of cell types, making it ideal for studies in cell biology and signal transduction pathways.CPNE2 is known for its role in calcium signaling and membrane trafficking, making it a key player in cellular function and regulation. Its involvement in these processes suggests potential implications in diseases related to disruptions in cellular homeostasis, such as cancer and neurological disorders.
By investigating CPNE2 activity, researchers can gain valuable insights into its functions and potential therapeutic targets for various conditions.Overall, the CPNE2 Polyclonal Antibody is a valuable tool for researchers delving into the intricate mechanisms of CPNE2 and its impact on cellular functions. Its high reactivity and specificity make it a reliable choice for studies aiming to uncover the complexities of CPNE2-mediated pathways and their relevance in various disease contexts.
Immunohistochemistry of paraffin-embedded human brain tissue using PACO38718 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human breast cancer using PACO38718 at dilution of 1:100.
Background:
Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Exhibits calcium-dependent cell membrane binding properties.
Synonyms:
Copine-2 (Copine II), CPNE2
UniProt Protein Function:
CPNE2: Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. Sequence analysis identified multiple alternatively spliced transcript variants but their full-length natures could not be determined. [provided by RefSeq, Jul 2008]Chromosomal Location of Human Ortholog: 16q13Cellular Component: cytoplasm; nucleus; plasma membraneMolecular Function: protein binding
UniProt Protein Details:
NCBI Summary:
Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. Sequence analysis identified multiple alternatively spliced transcript variants but their full-length natures could not be determined. [provided by RefSeq, Jul 2008]