The CPEB3 Polyclonal Antibody (CAB15402) is a valuable tool for researchers studying the role of CPEB3, a RNA binding protein involved in the regulation of mRNA translation and synaptic plasticity. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it a reliable choice for Western blot applications.CPEB3 is known for its function in controlling the translation of specific mRNAs in response to synaptic activity, contributing to long-lasting changes in neuronal connections. Dysregulation of CPEB3 has been implicated in neurological disorders such as Alzheimer's disease and intellectual disabilities, highlighting its importance in neuronal function and cognitive processes.
By targeting CPEB3, researchers can investigate the molecular mechanisms underlying synaptic plasticity and memory formation, providing insights into neurological conditions and potential therapeutic strategies. The CPEB3 Polyclonal Antibody is a versatile tool for studying this critical protein in various cellular contexts, advancing our understanding of synaptic function and brain disorders.
Product Name:
CPEB3 Rabbit Polyclonal Antibody
SKU:
CAB15402
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 150-400 of human CPEB3 (NP_055727.3).
Enables mRNA 3'-UTR binding activity and translation factor activity, RNA binding. Involved in cellular response to amino acid stimulus; negative regulation of transcription by RNA polymerase II; and positive regulation of mRNA catabolic process. Located in several cellular components, including cytosol; midbody; and nucleoplasm. Part of CCR4-NOT complex.
Purification Method:
Affinity purification
Gene ID:
22849
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat kidney using CPEB3 Rabbit pAb(CAB15402) at 1:1000 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection:ECL Basic Kit (AbGn00020).Exposuretime:1s.
