COPA Rabbit Polyclonal Antibody (CAB16821)
- SKU:
- CAB16821
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | COPA Rabbit Polyclonal Antibody |
SKU: | CAB16821 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 550-650 of human COPA (NP_001091868.1). |
Sequence: | FIYT TSNH IKYA VTTG DHGI IRTL DLPI YVTR VKGN NVYC LDRE CRPR VLTI DPTE FKFK LALI NRKY DEVL HMVR NAKL VGQS IIAY LQKK GYPE VALH F |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | AILJK; HEP-COP; alpha-COP; COPA |
Positive Sample: | Mouse liver |
Cellular Localization: | COPI vesicle coat, cytoplasm, cytosol, extracellular exosome, extracellular space, transport vesicle |
Calculated MW: | 138kDa |
Observed MW: | 110kDa |
In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms.
Purification Method: | Affinity purification |
Gene ID: | 1314 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |