The ColGALT1 Polyclonal Antibody (CAB16571) is a valuable tool for researchers studying ColGALT1, an enzyme involved in the biosynthesis of glycosaminoglycans, essential for extracellular matrix formation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to ColGALT1 protein, it enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in fields such as glycobiology, cancer research, and developmental biology.
ColGALT1 is a key enzyme in the process of glycosaminoglycan biosynthesis, impacting important cellular functions such as signaling, adhesion, and migration. Dysregulation of this enzyme has been implicated in various diseases, including cancer, genetic disorders, and developmental abnormalities. Therefore, understanding the role of ColGALT1 in these contexts is crucial for uncovering potential therapeutic targets and advancing our knowledge of disease mechanisms.
Product Name:
COLGALT1 Rabbit Polyclonal Antibody
SKU:
CAB16571
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-230 of human COLGALT1 (NP_078932.2).
The protein encoded by this gene is one of two enzymes that transfers galactose moieties to hydroxylysine residues of collagen and mannose binding lectin. This gene is constitutively expressed and encodes a soluble protein that localizes to the endoplasmic reticulum.
Purification Method:
Affinity purification
Gene ID:
79709
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of Mouse ovary, using COLGALT1 antibody (CAB16571) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
