The Coenzyme NAD+ Polyclonal Antibody is a valuable tool for researchers studying cellular metabolism and energy production. This antibody, raised in rabbits, specifically targets Coenzyme NAD+, a key player in various metabolic pathways including glycolysis, the citric acid cycle, and oxidative phosphorylation.Validated for use in Western blot applications, this antibody enables the detection and analysis of Coenzyme NAD+ levels in various cell types, making it ideal for studies in biochemistry, cell biology, and metabolic disorders. By measuring the levels of Coenzyme NAD+, researchers can gain insights into cellular energy production, redox signaling, and metabolic regulation.
Coenzyme NAD+ is essential for cellular processes such as DNA repair, gene expression, and aging, making it a crucial molecule to study in the context of diseases like cancer, neurodegenerative disorders, and metabolic syndromes. Understanding the role of Coenzyme NAD+ in these conditions can lead to the development of novel therapeutic strategies targeting cellular metabolism and energy balance.
Product Name:
Coenzyme NAD Polyclonal Antibody
SKU:
CAB21048
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Species independent
Immunogen:
NAD
Tested Applications:
ELISADB
Recommended Dilution:
DB,1:500 - 1:1000
Conjugate:
Unconjugated
Observed MW:
Refer to figures
NAD+, as a key coenzyme in eukaryotic organisms, determines hundreds of enzymatic reactions. The coenzyme NAD is involved in oxidation–reduction reactions critical for glycolysis, fatty acid oxidation, the TCA cycle, and complex I of the mitochondrial respiratory chain and also is a key regulator of autophagy. In addition, NAD+ can also indirectly regulate the process of anti-stress, cell growth, anti-inflammatory and anti-aging processes by regulating the function of Sirtuins factor which has NAD+ dependent protein deacetylation activity. The decline of NAD+ level will also lead to heart failure and Alzheimer's disease.
Purification Method:
Affinity purification
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Dot-blot analysis of all sorts of chemical compounds using Coenzyme NAD antibody (CAB21048) at 1:1000 dilution.
