The CLDN2 Polyclonal Antibody (CAB14085) is a valuable tool for researchers studying CLDN2, a tight junction protein that plays a crucial role in maintaining the integrity of epithelial barriers. This antibody, produced in rabbits, specifically targets the CLDN2 protein and is highly reactive with human samples, making it ideal for immunohistochemistry and other relevant applications.CLDN2 is known for its involvement in various physiological and pathological processes, including renal reabsorption, intestinal barrier function, and cancer progression.
By targeting CLDN2 with this antibody, researchers can gain valuable insights into the role of this protein in different cellular contexts, paving the way for potential therapeutic interventions targeting CLDN2-related pathways.With its high specificity and sensitivity, the CLDN2 Polyclonal Antibody (CAB14085) offers a reliable tool for researchers investigating the functions of CLDN2 and its potential implications in disease development and progression.
Product Name:
CLDN2 Rabbit Polyclonal Antibody
SKU:
CAB14085
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 184-230 of human CLDN2 (NP_001164563.1).
This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
9075
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of Rat liver, using CLDN2 antibody (CAB14085) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
