The CHPF2 Polyclonal Antibody (PACO4642) is a vital tool for researchers studying CHPF2, a protein involved in the glycosylation process of various cellular proteins. This antibody, generated in rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications. By binding to the CHPF2 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an essential component in studies related to cell biology and protein modification.CHPF2 plays a crucial role in the glycosylation pathway, which is essential for proper protein function and cellular communication. Dysregulation of glycosylation processes can lead to various diseases, including cancer, neurodegenerative disorders, and metabolic syndromes.
By understanding the function of CHPF2, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially develop targeted therapies to treat them.Overall, the CHPF2 Polyclonal Antibody is a valuable tool for researchers interested in exploring the role of glycosylation in cellular processes and its implications for human health. Its high reactivity and specificity make it a reliable asset for advancing our understanding of protein modification and its impact on disease development and progression.
Antibody Name:
CHPF2 Antibody
Antibody SKU:
PACO04642
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the N-terminal region of human CSGlcA-T.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
CSGlcA-T: Transfers glucuronic acid (GlcUA) from UDP-GlcUA to N- acetylgalactosamine residues on the non-reducing end of the elongating chondroitin polymer. Has no N- acetylgalactosaminyltransferase activity. Belongs to the chondroitin N- acetylgalactosaminyltransferase family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Glycan Metabolism - chondroitin sulfate biosynthesis; EC 2.4.1.226; TransferaseChromosomal Location of Human Ortholog: 7q36.1Cellular Component: Golgi membrane; membrane; integral to membraneMolecular Function: N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity; acetylgalactosaminyltransferase activityBiological Process: chondroitin sulfate metabolic process; chondroitin sulfate biosynthetic process; glycosaminoglycan metabolic process; carbohydrate metabolic process; pathogenesis
