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CHPF Antibody (PACO23799)

SKU:
PACO23799
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
IF
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
  • CHPF Antibody PACO23799
  • CHPF Antibody PACO23799
  • CHPF Antibody PACO23799
€419
Frequently bought together:

Description

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CHPF Antibody (PACO23799)

The CHPF Polyclonal Antibody (PAC023799) is a valuable tool for researchers studying the CHPF protein, which plays a key role in various cellular processes. This antibody, produced using rabbits, shows high reactivity with human samples and is validated for use in Western blot applications. By binding to the CHPF protein, researchers can accurately detect and analyze its expression in different cell types, making it an essential component for studies in cell biology and cancer research.

CHPF, also known as chondrocyte protein with a polyproline II helix motif, is involved in important cellular functions such as cell growth, differentiation, and apoptosis. Its involvement in these processes highlights its potential significance in diseases like cancer, where dysregulation of cell growth and apoptosis pathways can lead to tumorigenesis. Understanding the role of CHPF is crucial for developing targeted therapies that can manipulate these pathways for therapeutic benefit.

Antibody Name:CHPF Antibody (PACO23799)
Antibody SKU:PACO23799
Size:100ul
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC, IF
Recommended Dilutions:ELISA:1:2000-1:10000, WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500
Species Reactivity:Human, Mouse, Rat
Immunogen:Synthesized peptide derived from internal of human CHSS2.
Form:Liquid
Storage Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageWestern blot analysis of extracts from LOVO cells and K562 cells, using CHSS2 antibody.
Product ImageImmunofluorescence analysis of MCF-7 cells, using CHSS2 antibody.
Product ImageImmunohistochemistry analysis of paraffin-embedded human cervix carcinoma tissue using CHSS2 antibody.
Background:Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Isoform 2 may facilitate PARK2 transport into the mitochondria. In collaboration with PARK2, isoform 2 may enhance cell viability and protect cells from oxidative stress.
Synonyms:CHSS2; DKFZP434E0423; EC 2.4.1.175; EC 2.4.1.226;
UniProt Protein Function:CHPF: a type II transmembrane protein. May act as a specific activating factor for chondroitin synthase in chondroitin biosynthesis and polymerization. Protein type: Glycan Metabolism - chondroitin sulfate biosynthesis; EC 2.4.1.226; EC 2.4.1.175; Membrane protein, integral; TransferaseChromosomal Location of Human Ortholog: 2q35Cellular Component: Golgi membraneMolecular Function: glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activityBiological Process: chondroitin sulfate biosynthetic process
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q8IZ52
NCBI GenInfo Identifier:311033361
NCBI Gene ID:79586
NCBI Accession:Q8IZ52.2
UniProt Secondary Accession:Q8IZ52,Q6UXD6, Q7L4G1, Q9H0F8, Q9H618, B4DXU0
UniProt Related Accession:Q8IZ52
Molecular Weight:68,341 Da
NCBI Full Name:Chondroitin sulfate synthase 2
NCBI Synonym Full Names:chondroitin polymerizing factor
NCBI Official Symbol:CHPF  
NCBI Official Synonym Symbols:CSS2; CHSY2  
NCBI Protein Information:chondroitin sulfate synthase 2
UniProt Protein Name:Chondroitin sulfate synthase 2
UniProt Synonym Protein Names:Chondroitin glucuronyltransferase 2; Chondroitin-polymerizing factor; ChPF; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II; N-acetylgalactosaminyltransferase 2
Protein Family:Chondroitin sulfate synthase
UniProt Gene Name:CHPF  
UniProt Entry Name:CHSS2_HUMAN
AntibodiesELISA Kits
CHPF Antibody (PACO05365)Human CHPF (Chondroitin sulfate synthase 2) ELISA Kit (HUFI07961)
CHPF Antibody (PACO08417)
Secondary Antibody
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)
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