CHD3 Rabbit Polyclonal Antibody (CAB2221)
- SKU:
- CAB2221
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | CHD3 Rabbit Polyclonal Antibody |
SKU: | CAB2221 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1900-2000 of human CHD3 (NP_001005273.1). |
Sequence: | ERSI LSRL ASKG TEPH PTPA YPPG PYAT PPGY GAAF SAAP VGAL AAAG ANYS QMPA GSFI TAAT NGPP VLVK KEKE MVGA LVSD GLDR KEPR AGEV ICID D |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:1000 |
Synonyms: | ZFH; Mi-2a; SNIBCPS; Mi2-ALPHA; CHD3 |
Positive Sample: | Jurkat,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center. |
Calculated MW: | 227kDa |
Observed MW: | 280kDa |
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
Purification Method: | Affinity purification |
Gene ID: | 1107 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |