The CGB Antibody (PAC016020) is a high-quality polyclonal antibody designed for research involving the CGB protein, a marker of trophoblast cells in human placenta. Raised in rabbits, this antibody is highly reactive with human samples and is validated for use in various immunoassays, including Western blot and immunohistochemistry applications. It specifically binds to the CGB protein, allowing for accurate detection and analysis in biological samples.CGB, also known as chorionic gonadotropin subunit beta, is a hormone produced by trophoblast cells during pregnancy and plays a crucial role in maintaining pregnancy and supporting fetal development. Its detection and quantification are essential for understanding reproductive health and diagnosing pregnancy-related disorders.
The CGB Antibody is a valuable tool for researchers studying fertility, pregnancy, and reproductive disorders, providing insights into the role of CGB in these processes.With its high specificity and sensitivity, the CGB Antibody is ideal for use in immunological and reproductive research, offering reliable results and contributing to advancements in understanding the complex mechanisms of pregnancy and fertility regulation. Researchers can trust this antibody to deliver accurate and reproducible data for their studies in reproductive biology and related fields.
Antibody Name:
CGB Antibody (PACO16020)
Antibody SKU:
PACO16020
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:50-1:200
Species Reactivity:
Human
Immunogen:
Fusion protein of human CGB
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO16020(CGB Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO16020(CGB Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200).
Background:
This gene is a member of the glycoprotein hormone β chain family and encodes the β 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common α subunit and an unique β subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.
Synonyms:
chorionic gonadotropin, β polypeptide
UniProt Protein Function:
CGB: Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. Belongs to the glycoprotein hormones subunit beta family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:
Protein type:Secreted, signal peptide; Inhibitor; Secreted
Chromosomal Location of Human Ortholog: 19q13.32
NCBI Summary:
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 8 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]
