The CES1c Polyclonal Antibody (PAC03470) is a valuable tool for researchers studying CES1c, an enzyme involved in drug metabolism and lipid homeostasis. This antibody, generated in rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications. By binding to the CES1c protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for investigations in pharmacology and lipid metabolism.CES1c, also known as carboxylesterase 1C, plays a crucial role in the metabolism of various drugs, including anti-cancer agents and cardiovascular medications.
Additionally, it is involved in lipid digestion and absorption, making it a potential target for therapies addressing metabolic disorders and drug interactions. Research on CES1c is essential for understanding its impact on drug efficacy and metabolism, as well as its potential implications for personalized medicine and treatment strategies.
Western blot. All lanes: Ces1c antibody at 2µg/ml. Lane 1: Mouse liver tissue. Lane 2: Rat liver tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 62 kDa. Observed band size: 62 kDa.
Immunohistochemistry of paraffin-embedded human colon cancer using PACO34470 at dilution of 1:10.
Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO34470 at dilution of 1:10.
Background:
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant.
