The CEP192 Polyclonal Antibody (PAC048050) is a cutting-edge research tool designed for the study of CEP192, a centrosome protein critical for cell division and organization. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for use in a variety of research applications, including Western blotting and immunofluorescence.CEP192 is a key player in centrosome biogenesis and function, regulating processes such as microtubule organization and spindle assembly during cell division. Dysregulation of CEP192 has been linked to abnormal cell division and genome instability, making it a potential target for cancer research and therapy development.
By enabling precise detection and analysis of CEP192 protein levels in different cell types, this antibody empowers researchers to explore the role of CEP192 in various physiological and pathological conditions.The unique properties of the CEP192 Polyclonal Antibody (PAC048050), coupled with its versatility in different experimental settings, make it a valuable tool for scientists investigating the intricate mechanisms of centrosome biology and its impact on cell physiology. Whether studying cell cycle progression, mitotic spindle formation, or centrosome dynamics, this antibody provides reliable and accurate results, advancing our understanding of fundamental cellular processes.
Immunohistochemistry of paraffin-embedded human testis tissue using PACO48050 at dilution of 1:100.
Immunofluorescent analysis of Hela cells using PACO48050 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
Required for mitotic centrosome and spindle assembly. Appears to be a major regulator of pericentriolar material (PCM) recruitment, centrosome maturation, and centriole duplication.
Synonyms:
Centrosomal protein of 192 kDa (Cep192), CEP192, KIAA1569
UniProt Protein Function:
Function: Required for mitotic centrosome and spindle assembly. Appears to be a major regulator of pericentriolar material (PCM) recruitment, centrosome maturation, and centriole duplication.2 PublicationsManual assertion based on experiment in:Ref.9
