The CDKB1/2 Antibody (PACO35874) is a polyclonal antibody specifically designed for research involving CDKB1/2, a pair of cyclin-dependent kinases essential for cell cycle progression. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the CDKB1/2 proteins, this antibody enables accurate detection and analysis in a variety of cell types, making it an excellent tool for studies in cell biology, cancer research, and drug development.CDKB1/2, also known as cyclin-dependent kinase 1 and 2, play a crucial role in regulating cell division and proliferation by controlling the progression through different phases of the cell cycle.
Dysregulation of CDKB1/2 activity has been implicated in various diseases, including cancer, making it a promising target for therapeutic interventions. Understanding the functions and mechanisms of CDKB1/2 can provide valuable insights into the development of novel treatments for cancer and other proliferative disorders.Overall, the CDKB1/2 Antibody (PACO35874) offers researchers a reliable tool to investigate the role of CDKB1/2 in cell cycle regulation and disease pathogenesis, ultimately contributing to advancements in the field of molecular biology and biomedicine.
Antibody Name:
CDKB1-2 Antibody (PACO35874)
Antibody SKU:
PACO35874
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Arabidopsis thaliana
Immunogen:
Recombinant Arabidopsis thaliana Cyclin-dependent kinase B1-2 protein (1-311AA)
Together with CDKB1-1, promotes both the last division in the stomatal cell lineage as well as the number of stomata. In collaboration with MYB124 and MYB88, restrict the G1/S transition and chloroplast and nuclear number during stomatal formation, and normally maintain fate and developmental progression throughout the stomatal cell lineage.
Together with CDKB1-1, promotes both the last division in the stomatal cell lineage as well as the number of stomata (PubMed:20675570). In collaboration with MYB124 and MYB88, restrict the G1/S transition and chloroplast and nuclear number during stomatal formation, and normally maintain fate and developmental progression throughout the stomatal cell lineage (PubMed:24123248).
UniProt Protein Details:
NCBI Summary:
Encodes a member of a plant specific family of cyclin dependent kinases.
