The CDK2AP2 Polyclonal Antibody (PAC021705) is a valuable tool for research involving CDK2AP2, a protein that plays a role in cell cycle regulation and tumor suppression. This antibody, generated in rabbits, is highly specific for human samples and is validated for use in Western blot applications. It binds specifically to the CDK2AP2 protein, allowing for the detection and analysis of CDK2AP2 expression in various cell types.CDK2AP2, also known as CDK2-associated protein 2, is involved in the regulation of Cyclin-dependent kinase 2 (CDK2) activity and has been implicated in the inhibition of cell proliferation and tumor growth. Its importance in cell cycle control and tumor suppression makes CDK2AP2 a key target for research in cancer biology and therapeutic development.
By studying the function and expression of CDK2AP2, researchers can gain valuable insights into its role in cell growth and potential as a target for cancer treatment strategies. Overall, the CDK2AP2 Polyclonal Antibody is a reliable tool for investigating the function of CDK2AP2 in various biological processes, particularly in the context of cancer research and cell cycle regulation. Its specificity and sensitivity make it an ideal choice for researchers studying the role of CDK2AP2 in tumor suppression and cell proliferation pathways.
Antibody Name:
CDK2AP2 Antibody (PACO21705)
Antibody SKU:
PACO21705
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:50-1:100
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from internal of human CDKA2.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CDKA2 antibody.
Background:
Belongs to the CDK2AP family. Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Synonyms:
Cyclin-dependent kinase 2-associated protein 2; CDK2-associated protein 2; DOC-1-related protein; DOC-1R; CDK2AP2
UniProt Protein Function:
CDK2AP2: Belongs to the CDK2AP family.Protein type: Cell cycle regulationChromosomal Location of Human Ortholog: 11q13
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein that interacts with cyclin-dependent kinase 2 associated protein 1. Pseudogenes associated with this gene are located on chromosomes 7 and 9. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]
