The CD82 Antigen Polyclonal Antibody (CAB1778) is a valuable tool for research involving the CD82 antigen, a cell surface protein involved in cell adhesion and signaling. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in various applications, including Western blotting. It binds specifically to the CD82 antigen, allowing for detection and analysis in different cell types, making it ideal for studies in cell biology and cancer research.The CD82 antigen, also known as KAI1, plays a crucial role in cell migration, invasion, and metastasis, making it a potential target for cancer therapy and drug development.
Its involvement in cell-to-cell communication and signaling pathways also makes it relevant in the study of various physiological and pathological processes. Research into the function and regulation of the CD82 antigen is essential for understanding its potential role in cancer progression and as a therapeutic target for cancer treatment.
Product Name:
CD82 Rabbit Polyclonal Antibody
SKU:
CAB1778
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human CD82 (NP_002222.1).
This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3732
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from MCF7 cells, using CD82 Rabbit pAb (CAB1778) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
