The CD53 Polyclonal Antibody (CAB10007) is a valuable tool for researchers studying the CD53 protein, a cell surface molecule involved in immune regulation and cellular communication. This polyclonal antibody, generated in rabbits, is highly specific and sensitive to human samples, making it ideal for a variety of research applications.CD53, a member of the tetraspanin family, plays a significant role in immune cell activation, migration, and signaling. Its involvement in various physiological processes makes it a key target for investigations in immunology, infectious diseases, and cancer research.
The CD53 Polyclonal Antibody enables researchers to detect and analyze CD53 expression in different cell types, providing valuable insights into its function and potential therapeutic implications.By utilizing this antibody in techniques such as Western blotting and immunofluorescence, researchers can advance their understanding of CD53's role in immune responses, cellular adhesion, and signal transduction pathways. This antibody is a reliable tool for exploring the potential of CD53 as a diagnostic marker or therapeutic target in various disease states.
Product Name:
CD53 Polyclonal Antibody
SKU:
CAB24527
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 107-181 of mouse CD53 (NP_031677.1).
Predicted to enable identical protein binding activity. Involved in positive regulation of myoblast fusion. Located in cell-cell junction and plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human CD53 (CD53 molecule).
Purification Method:
Affinity purification
Gene ID:
12508
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of Mouse spleen, using CD53 Rabbit pAb (CAB24527) at 1:800 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.