CD53 Rabbit Polyclonal Antibody (CAB10079)
- SKU:
- CAB10079
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | CD53 Rabbit Polyclonal Antibody |
SKU: | CAB10079 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-180 of human CD53 (NP_000551.1). |
Sequence: | AILL FVYE QKLN EYVA KGLT DSIH RYHS DNST KAAW DSIQ SFLQ CCGI NGTS DWTS GPPA SCPS DRKV EGCY AKAR LWFH S |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:4000 |
Synonyms: | MOX44; TSPAN25; CD53 |
Positive Sample: | Mouse spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Membrane, Multi-pass membrane protein. |
Calculated MW: | 24kDa |
Observed MW: | 35-45kDa |
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 963 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |