The CD302 Polyclonal Antibody (PAC037874) is a valuable tool for researchers studying the CD302 protein, a cell surface molecule involved in immune regulation. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By binding to CD302, this antibody enables the detection and analysis of the protein in various cell types, making it ideal for research in immunology and cancer.CD302, also known as an immune inhibitory receptor, plays a crucial role in immune homeostasis by regulating inflammation and inhibiting allergic reactions.
Its significance in immune response modulation makes it a promising target for studying diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the function of CD302 is instrumental in the development of therapies aimed at modulating immune responses in these disease contexts.
Potential multifunctional C-type lectin receptor that may play roles in endocytosis and phagocytosis as well as in cell adhesion and migration.
Synonyms:
CD302 antigen (C-type lectin BIMLEC) (C-type lectin domain family 13 member A) (DEC205-associated C-type lectin 1) (Type I transmembrane C-type lectin receptor DCL-1) (CD antigen CD302), CD302, CLEC13A DCL1 KIAA0022
UniProt Protein Function:
CD302: Potential multifunctional C-type lectin receptor that may play roles in endocytosis and phagocytosis as well as in cell adhesion and migration. 5 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 2q24.2Cellular Component: cell cortex; filopodium; membraneBiological Process: phagocytosis
UniProt Protein Details:
NCBI Summary:
CD302 is a C-type lectin receptor involved in cell adhesion and migration, as well as endocytosis and phagocytosis (Kato et al., 2007 [PubMed 17947679]).[supplied by OMIM, Aug 2008]
