The CD146 (MCAM) Polyclonal Antibody is a powerful tool for researchers studying CD146, a cell adhesion molecule also known as Melanoma Cell Adhesion Molecule. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been specifically validated for Western blot applications.CD146 plays a crucial role in various biological processes, including cell adhesion, migration, and signaling, making it a key player in cancer progression, angiogenesis, and tissue regeneration. The CD146 Polyclonal Antibody binds specifically to CD146 protein, enabling precise detection and analysis in a variety of cell types.
Researchers in the fields of immunology, cancer biology, and regenerative medicine will find the CD146 Polyclonal Antibody invaluable in their studies. By understanding the function and regulation of CD146, researchers can uncover new insights into the pathogenesis of diseases such as cancer and identify potential therapeutic targets for intervention.Enhance your research with the CD146 (MCAM) Polyclonal Antibody and unlock the potential of CD146 as a biomarker and therapeutic target in various diseases.
Product Name:
CD146/MCAM Polyclonal Antibody
SKU:
CAB21488
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 447-646 of human CD146/MCAM (NP_006491.2).
Involved in glomerular filtration and vascular wound healing. Acts upstream of or within angiogenesis. Located in external side of plasma membrane. Biomarker of chronic obstructive pulmonary disease and uveal melanoma.
Purification Method:
Affinity purification
Gene ID:
4162
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CD146/MCAM antibody (CAB21488) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
