The CCDC28B Polyclonal Antibody (PACO8227) is a valuable tool for researchers studying CCDC28B, a protein involved in cell cycle regulation and DNA damage response. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot applications. By binding to the CCDC28B protein, this antibody allows for precise detection and analysis in various cell types, making it an ideal choice for studies in molecular biology, cancer research, and genomics.CCDC28B, also known as coiled-coil domain containing 28B, plays a crucial role in maintaining genomic stability and cell division processes. Its function in DNA repair pathways and cell cycle progression makes it a key player in cellular health and disease development.
Research on CCDC28B can provide insights into mechanisms of cancer development, genetic disorders, and cellular response to environmental stressors.By using the CCDC28B Polyclonal Antibody, researchers can further investigate the biological functions and signaling pathways associated with CCDC28B, paving the way for potential therapeutic advancements in cancer treatment and genetic diseases. Understanding the role of CCDC28B in cellular processes is essential for developing targeted therapies and personalized medicine strategies in the future.
CCDC28B: Involved in ciliogenesis. Interacts with BBS1, BBS2, BBS4, BBS5, BBS6, BBS7 AND BBS8Chromosomal Location of Human Ortholog: 1p36.11-p34.2Cellular Component: centrosome; cytoplasmMolecular Function: protein bindingBiological Process: cilium biogenesisDisease: Bardet-biedl Syndrome 1
UniProt Protein Details:
NCBI Summary:
The product of this gene localizes to centrosomes and basal bodies. The protein colocalizes with several proteins associated with Bardet-Biedl syndrome (BBS) and participates in the regulation of cilia development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
