The CAPRIN1 Polyclonal Antibody (PACO36310) is a valuable tool for researchers studying CAPRIN1, a key protein involved in RNA regulation and cellular processes. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By targeting the CAPRIN1 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an essential component for studies in molecular biology and medical research.CAPRIN1 is known to be crucial for cellular functions such as mRNA translation and stress granule formation, making it a significant player in gene expression regulation.
Its involvement in RNA metabolism implicates it in a range of cellular activities, including cell growth, apoptosis, and response to environmental stress. As such, understanding the role of CAPRIN1 is essential for unraveling its implications in diseases like cancer, neurological disorders, and viral infections.By using the PACO36310 antibody, researchers can delve into the mechanisms underlying CAPRIN1's functions and explore its potential as a therapeutic target. This antibody opens up possibilities for investigating the impact of CAPRIN1 on cellular processes and disease pathways, paving the way for new insights and developments in biomedical research.
May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.
Synonyms:
Caprin-1 (Cytoplasmic activation- and proliferation-associated protein 1) (GPI-anchored protein p137) (GPI-p137) (p137GPI) (RNA granule protein 105), Caprin1, Gpiap1 Rng105
UniProt Protein Function:
May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types.
