The Calpain-5 Polyclonal Antibody (CAB7428) is a crucial tool for researchers studying calpain-5, a protein involved in cellular processes such as signaling, differentiation, and apoptosis. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to calpain-5, this antibody enables accurate detection and analysis in various cell types, making it an ideal choice for studies in molecular biology and cell signaling pathways.Calpain-5, also known as calcium-dependent cysteine protease, is a key player in regulating cell growth and survival through its ability to cleave specific protein targets. Its diverse functions make it a promising target for research into diseases such as cancer, neurodegenerative disorders, and diabetes.
Understanding the role of calpain-5 in these conditions is crucial for developing targeted therapies that impact cellular processes and promote health and well-being.Overall, the Calpain-5 Polyclonal Antibody (CAB7428) is an essential tool for researchers looking to delve deep into the intricate workings of calpain-5 and its implications in various cellular processes and disease states. By enabling accurate detection and analysis of this protein, this antibody opens up new avenues for exploration and discovery in the field of molecular biology and biomedical research.
Product Name:
CAPN5 Rabbit Polyclonal Antibody
SKU:
CAB7428
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 361-640 of human CAPN5 (NP_004046.2).
Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. A functional calpain protein consists of an invariant small subunit and 1 of a family of large subunits. CAPN5 is one of the large subunits. Unlike some of the calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Because of the significant similarity to Caenorhabditis elegans sex determination gene tra-3, CAPN5 is also called as HTRA3.
Purification Method:
Affinity purification
Gene ID:
726
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CAPN5 antibody (CAB7428) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
