The CABP2 Polyclonal Antibody (PACO51058) is a valuable tool for researchers studying CABP2, a calcium-binding protein involved in various cellular processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the CABP2 protein, researchers can detect and analyze its expression in different cell types, making it a versatile tool for studies in neuroscience and cell biology.CABP2, also known as calcium-binding protein 2, plays a crucial role in calcium signaling pathways that are essential for neurotransmission and synaptic plasticity.
Its involvement in these processes makes it a promising target for research into neurological disorders, such as Alzheimer's disease and epilepsy. Understanding the function of CABP2 is key to developing therapies that target calcium signaling pathways in the brain.Overall, the PACO51058 antibody offers researchers a reliable and specific tool for investigating the role of CABP2 in cellular processes and neurological disorders, ultimately contributing to advancements in the field of neuroscience research.
Antibody Name:
CABP2 Antibody (PACO51058)
Antibody SKU:
PACO51058
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:2000-1:10000, IF:1:50-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Calcium-binding protein 2 protein (6-172AA)
Immunofluorescent analysis of HepG2 cells using PACO51058 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
Golgi apparatus, plasma membrane, calcium ion binding, signal transduction
Synonyms:
Calcium-binding protein 2 (CaBP2), CABP2
UniProt Protein Function:
CABP2: 2 isoforms of the human protein are produced by alternative splicing.Protein type: Calcium-bindingChromosomal Location of Human Ortholog: 11q13.1Cellular Component: Golgi apparatus; perinuclear region of cytoplasm; plasma membraneMolecular Function: calcium ion bindingBiological Process: signal transductionDisease: Deafness, Autosomal Recessive 93
UniProt Protein Details:
NCBI Summary:
This gene belongs to a subfamily of calcium binding proteins that share similarity to calmodulin. Like calmodulin, these family members can likely stimulate calmodulin-dependent kinase II and the protein phosphatase calcineurin. Calcium binding proteins are an important component of calcium mediated cellular signal transduction. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
