The BLVRA Polyclonal Antibody (CAB3765) is a valuable tool for researchers studying the BLVRA protein, which plays a crucial role in heme degradation and redox balance. This antibody is produced in rabbits and has been extensively validated for Western blot applications, ensuring reliable and accurate results in detecting BLVRA protein levels in a variety of samples.BLVRA, also known as biliverdin reductase A, is an enzyme that converts biliverdin to bilirubin, a process essential for maintaining proper heme levels and antioxidant defense in the body. Dysregulation of BLVRA has been linked to various diseases, including cancer, cardiovascular disorders, and neurodegenerative conditions.
By using the BLVRA Polyclonal Antibody, researchers can gain insight into the role of BLVRA in these diseases and potentially develop targeted therapies to modulate its activity.With its high reactivity with human samples and specificity for the BLVRA protein, this antibody is an invaluable tool for studying the function and regulation of BLVRA in health and disease. It is particularly useful in research areas such as biochemistry, molecular biology, and pharmacology, where understanding the mechanisms of heme metabolism and redox signaling is crucial for advancing scientific knowledge and developing novel therapeutic strategies.
Product Name:
BLVRA Rabbit Polyclonal Antibody
SKU:
CAB3765
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-296 of human BLVRA (NP_001240752.1).
The protein encoded by this gene belongs to the biliverdin reductase family, members of which catalyze the conversion of biliverdin to bilirubin in the presence of NADPH or NADH. Mutations in this gene are associated with hyperbiliverdinemia. Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
644
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse kidney, using BLVRA antibody (CAB3765) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 90s.
