The BEPA Antibody (PAC062179) is a valuable tool for researchers studying BEPA, a protein involved in immune regulation and inflammatory responses. This rabbit polyclonal antibody is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the BEPA protein, researchers can detect and analyze its expression in various cell types, making it an ideal choice for studies in immunology and inflammatory conditions.
BEPA, also known as an immune regulatory protein, plays a key role in modulating immune responses and controlling inflammation. Understanding the function of BEPA is crucial for developing new therapies for diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. By targeting BEPA, researchers can potentially design treatments that harness or modulate immune responses to improve patient outcomes in these disease contexts.
Antibody Name:
bepA Antibody (PACO62179)
Antibody SKU:
PACO62179
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:
Escherichia coli
Immunogen:
Recombinant Escherichia coli Beta-barrel assembly-enhancing protease protein (214-487AA)
Western Blot. Positive WB detected in Recombinant protein. All lanes: bepA antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 35 kDa. Observed band size: 37 kDa.
Background:
Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state. Promotes disulfide rearrangement of LptD during its biogenesis, and proteolytic degradation of LptD and BamA when their proper assembly is compromised. May facilitate membrane attachment of LoiP under unfavorable conditions.
Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state. Promotes disulfide rearrangement of LptD during its biogenesis, and proteolytic degradation of LptD and BamA when their proper assembly is compromised. May facilitate membrane attachment of LoiP under unfavorable conditions.
UniProt Protein Details:
NCBI Summary:
Overexpression causes abnormal biofilm architecture. [More information is available at EcoGene: EG14199].
