The B3GNT3 Polyclonal Antibody (CAB17611) is a valuable tool for researchers studying B3GNT3, an enzyme involved in the biosynthesis of glycosphingolipids. This rabbit polyclonal antibody is highly specific and reacts strongly with human samples, making it ideal for use in a variety of research applications, including Western blotting.B3GNT3 plays a crucial role in glycosylation processes that are essential for normal cellular functions, including cell adhesion, signaling, and immune response regulation.
Dysregulation of B3GNT3 has been implicated in various diseases, such as cancer, diabetes, and neurological disorders. By using the B3GNT3 Polyclonal Antibody, researchers can investigate the expression and function of B3GNT3 in different cell types and tissues, providing valuable insights into its role in health and disease.
Product Name:
B3GNT3 Rabbit Polyclonal Antibody
SKU:
CAB17611
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 120-240 of human B3GNT3 (NP_055071.2).
This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein and contains a signal anchor that is not cleaved. It prefers the substrates of lacto-N-tetraose and lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains and the biosynthesis of the backbone structure of dimeric sialyl Lewis a. It plays dominant roles in L-selectin ligand biosynthesis, lymphocyte homing and lymphocyte trafficking.
Purification Method:
Affinity purification
Gene ID:
10331
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using B3GNT3 Rabbit pAb (CAB17611) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
