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B3GALT2 Antibody (PACO25184)

SKU:
PACO25184
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
IHC
IF
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
  • B3GALT2 Antibody PACO25184
  • B3GALT2 Antibody PACO25184
  • B3GALT2 Antibody PACO25184
€339
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Description

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B3GALT2 Antibody (PACO25184)

The B3GALT2 Monoclonal Antibody (PACO25184) is a valuable tool for researchers studying B3GALT2, an enzyme involved in the biosynthesis of glycoproteins and glycolipids. This antibody, generated in mice, exhibits high specificity and sensitivity for human samples and has been validated for use in various applications, including Western blotting and immunofluorescence.B3GALT2 plays a crucial role in the glycosylation process, which is essential for proper cell function and signaling. Dysregulation of this enzyme has been linked to various diseases, including cancer and congenital disorders.

By targeting B3GALT2 with this antibody, researchers can gain valuable insights into its function and potential implications in disease development and progression.This monoclonal antibody offers researchers a reliable tool for studying the role of B3GALT2 in cellular processes and disease pathways, making it an essential component for studies in glycobiology, cancer biology, and developmental biology. Its high specificity and sensitivity ensure accurate and reproducible results, providing a valuable resource for advancing scientific knowledge in these fields.

Antibody Name:B3GALT2 Antibody (PACO25184)
Antibody SKU:PACO25184
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, IHC, IF
Recommended Dilutions:ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200
Species Reactivity:Human
Immunogen:Recombinant Human Beta-1,3-galactosyltransferase 2 protein (201-422AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageImmunohistochemistry of paraffin-embedded human liver tissue using PACO25184 at dilution of 1:100.
Product ImageImmunofluorescence staining of A549 cells with PACO25184 at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Product ImageImmunohistochemistry of paraffin-embedded human heart tissue using PACO25184 at dilution of 1:100.
Background:Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N-acetylglucosamine (beta-GlcNAc) residue. Can also utilize substrates with a terminal galactose residue, albeit with lower efficiency. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues.
Synonyms:Beta-1,3-galactosyltransferase 2 (Beta-1,3-GalTase 2) (Beta3Gal-T2) (Beta3GalT2) (EC 2.4.1.86) (UDP-galactose:2-acetamido-2-deoxy-D-glucose 3beta-galactosyltransferase 2), B3GALT2
UniProt Protein Function:Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N-acetylglucosamine (beta-GlcNAc) residue. Can also utilize substrates with a terminal galactose residue, albeit with lower efficiency. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues.
NCBI Summary:This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene encodes a protein that functions in N-linked glycoprotein glycosylation and shows strict donor substrate specificity for UDP-galactose. [provided by RefSeq, Jul 2008]
UniProt Code:O43825
NCBI GenInfo Identifier:61211698
NCBI Gene ID:8707
NCBI Accession:O43825.1
UniProt Secondary Accession:O43825,Q9BZQ9, B2RAB1,
UniProt Related Accession:O43825
Molecular Weight:49,213 Da
NCBI Full Name:Beta-1,3-galactosyltransferase 2
NCBI Synonym Full Names:beta-1,3-galactosyltransferase 2
NCBI Official Symbol:B3GALT2  
NCBI Official Synonym Symbols:GLCT2; BETA3GALT2; beta3Gal-T2  
NCBI Protein Information:beta-1,3-galactosyltransferase 2
UniProt Protein Name:Beta-1,3-galactosyltransferase 2
UniProt Synonym Protein Names:UDP-galactose:2-acetamido-2-deoxy-D-glucose 3beta-galactosyltransferase 2
Protein Family:Beta-1,3-galactosyltransferase
UniProt Gene Name:B3GALT2  
AntibodiesELISA Kits
B3GALT2 Antibody (PACO05611)Human B3GALT2 / GLCT2 ELISA Kit
Secondary Antibody
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)
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