ATP6V1E1 Rabbit Polyclonal Antibody (CAB3756)
- SKU:
- CAB3756
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Description
Product Name: | ATP6V1E1 Rabbit Polyclonal Antibody |
SKU: | CAB3756 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 77-226 of human ATP6V1E1 (NP_001687.1). |
Sequence: | NQAR LKVL RARD DLIT DLLN EAKQ RLSK VVKD TTRY QVLL DGLV LQGL YQLL EPRM IVRC RKQD FPLV KAAV QKAI PMYK IATK NDVD VQID QESY LPED IAGG VEIY NGDR KIKV SNTL ESRL DLIA QQMM PEVR GALF GANA NRKF LD |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | P31; Vma4; ATP6E; ARCL2C; ATP6E2; ATP6V1E; ATP6V1E1 |
Positive Sample: | A-431,LO2,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | apical plasma membrane, cytosol, endosome, extracellular exosome, microvillus |
Calculated MW: | 26kDa |
Observed MW: | 31kDa |
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain E subunit isoforms. Pseudogenes for this gene have been found in the genome.
Purification Method: | Affinity purification |
Gene ID: | 529 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |