SERCA1/ATP2A1 Rabbit Polyclonal Antibody (CAB10104)
- SKU:
- CAB10104
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SERCA1/ATP2A1 Rabbit Polyclonal Antibody |
SKU: | CAB10104 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 901-1001 of human SERCA1/SERCA1/ATP2A1 (NP_775293.1). |
Sequence: | LSVL VTIE MCNA LNSL SENQ SLLR MPPW VNIW LLGS ICLS MSLH FLIL YVDP LPMI FKLR ALDL TQWL MVLK ISLP VIGL DEIL KFVA RNYL EDPE DERR K |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:1000 |
Synonyms: | ATP2A; SERCA1; SERCA1/ATP2A1 |
Positive Sample: | C2C12 |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Multi-pass membrane protein, Sarcoplasmic reticulum membrane. |
Calculated MW: | 110kDa |
Observed MW: | 110kDa |
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 487 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |