Description
Product Name: | ATG4A Polyclonal Antibody |
SKU: | CAB21356 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 289-398 of human ATG4A (NP_443168.2). |
Sequence: | TEEN GTVN DQTF HCLQ SPQR MNIL NLDP SVAL GFFC KEEK DFDN WCSL VQKE ILKE NLRM FELV QKHP SHWP PFVP PAKP EVTT TGAE FIDS TEQL EEFD LEED FEIL SV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | APG4A; AUTL2; HsAPG4A; ATG4A |
Positive Sample: | Jurkat,K-562,HeLa,Jurkat,HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 45kDa |
Observed MW: | 45kDa/50kDa |
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases.
Purification Method: | Affinity purification |
Gene ID: | 115201 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |